منابع مشابه
Cancer risk assessment of 1,3-butadiene.
This paper discusses the Environmental Protection Agency's (EPA) risk assessment of 1,3-butadiene. The assessment focuses on estimation of increased cancer risk to populations living near industrial sources of 1,3-butadiene emissions rather than occupationally exposed populations. Incremental cancer risk estimates based on extrapolation from laboratory animal data are presented. Pharmacokinetic...
متن کاملAssessment of thyroid cancer risk factors in Kurdistan province
ABSTRACT Background and Aim: Considering the increasing trend of thyroid cancer and increased number of new cases we performed this study to determine the risk factors for thyroid cancer in Kurdistan Province. Materials and Methods: 80 patients and 80 controls were matched and entered into this case-control study from September 2009 to September 2016 in Kurdistan Province. Data were colle...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssessment of 1,3-butadiene epidemiology studies.
Positive carcinogenicity studies in mice and rats have led to concerns that 1,3-butadiene may be carcinogenic in humans under exposure conditions that have existed in occupational settings and perhaps exist today. The principal settings of interest are the styrene-butadiene rubber (SBR) manufacturing industry, which uses large quantities of 1,3-butadiene, and the 1,3-butadiene monomer industry....
متن کاملThe use of non-tumor data in cancer risk assessment: reflections on butadiene, vinyl chloride, and benzene.
The estimation and characterization of a cancer risk is grounded in the observation of tumors in humans and/or experimental animals. Increasingly, however, other kinds of data (non-tumor data) are finding application in cancer risk assessment. Metabolism and kinetics, adduct formation, genetic damage, mode of action, and biomarkers of exposure, susceptibility, and effects are examples. While th...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1990
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.9086149